OPTIMUM food allergy trial

OPTIMUM food allergy trial


The number of children diagnosed with food allergies has risen greatly in Australia and around the world in the last 20 years.

There are many factors currently being investigated that may contribute to why so many more children have food allergies.

The OPTIMUM Study is looking to determine whether one dose of ‘whole cell’ pertussis (whooping cough) vaccine given at two months of age instead of the current ‘acellular’ pertussis vaccine can help protect young children against allergic outcomes.


Email: SCHN-OPTIMUM@health.nsw.gov.au 

Phone: 0423 799 327 (The Children's Hospital at Westmead)

Phone: 0418 411 602 (Sydney Children's Hospital, Randwick)

Who can take part

  • Healthy babies aged 6-12 weeks of age (born after 32 weeks gestation)
  • Living in Sydney

Who cannot participate

  • Babies who have already received their 6-8 week vaccines
  • Babies with other serious health issues
  • Babies where a food allergy has already been diagnosed

What happens in the study?

  • Participation will be for 18 months and will involve 3 study visits, including a free allergy test appointment at 1 year of age at The Children’s Hospital at Westmead and Sydney Children's Hospital, Randwick
  • Families will also be asked to complete 5 short online questionnaires over the course of the study
Last updated Monday 29th January 2024