Kids Cancer Centre Research
This page is a research page. For clinical information, please view our Kids Cancer Centre service page on the Sydney Children's Hospitals Network website.
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The Kids Cancer Centre (KCC) is a research-informed oncology clinical care service based at Sydney Children's Hospital, Randwick. With a long history of combining research with clinical care, we work to provide children with cancer and blood disorders the best chance of survival.
By partnering with leading specialists and organisations from across Australia and around the world, we access cutting-edge clinical care, clinical trials, and the latest programs and treatments, all in one place, to find innovative ways to diagnose, treat and cure childhood cancer and blood disorders.
We have three primary teams:
Impact
- We co-lead the ZERO Childhood Cancer program (ZERO) with the Children’s Cancer Institute, Australia’s first ever personalised medicine program for children with high-risk or relapsed cancer. The program has enrolled thousands of children with all cancer types and risk profiles. Using ZERO we found that just over half of children (55%) who received personalised cancer therapy achieved complete or partial remission, or had their disease stabilise for at least 6 months (PRISM/ZERO2).
- We developed an Australian-first clinical trial using CAR T-Cell Therapy to fight childhood brain cancer.
- We use new protocols that identify patients at higher risk of relapse to tailor treatment accordingly to prevent relapse and reduce side effects. Simultaneously we also identify patients who require less intensive therapy to achieve a cure, reducing their level of toxicity.
- Our psychosocial, health and lifestyle programs help detect and correct complications for childhood cancer survivors into their adulthood to unlock new ways to reduce the long-term effects of cancer treatment.
Collaborators
