The Neuropathy Research Group at Kids Neuroscience Centre comprises clinician-researchers and scientists aiming to improve the lives of children with Charcot-Marie-Tooth disease (CMT) and related neuropathies by developing and identifying validatinged scalesclinical outcome measures to measure the of disability caused by CMT, evaluating effective rehabilitative measures solutions including exercise and orthoses, identifying novel genetic causes of CMT, and investigating disease-modifying therapies through clinical trials.

CMT, otherwise referred to as an inherited peripheral neuropathy, is a common genetic disorder of the motor and sensory nerves. Symptoms first occur in childhood, and nerve degeneration results in weakness of the muscles of the hands and feet and loss of sensation.

While there is currently no curative therapy for CMT, a number of promising compounds have been identified and human trials are either underway or slated to begin.

At The Children’s Hospital at Westmead, children with CMT are evaluated in at the Peripheral Neuropathy Management Clinic (PNMC) which includes neurologists, allied health professionals, orthopaedic surgeons, rehabilitation paediatricians and research staff who are experts in CMT.

The PNMC has been identified as an international centre of excellence by the Charcot-Marie-Tooth Association of USA.

Collaborators