The Translational Neurogenomics Research Group's research lies primarily in understanding the mechanisms underlying neurological disorders using the latest technologies (e.g. next generation sequencing, 3D model systems and high-throughput in vitro functional assays). 

The team has collected and researched over 4,000 neurological disorder samples including startle disorder (or Hyperekplexia), focal and generalised epilepsy, plus 130 multiplex families with rare forms of epilepsy syndromes. Their research findings in rare genetic disorders, such as hyperekplexia, LQTS syndrome and epileptic encephalopathy, have expanded the repertoire of disease genes and identified new mechanisms linked to disease onset.

The team is currently developing the next-generation methodology including the rescue-modelling adjunct to gene-discovery and in vitro functional characterisation of variants in protein-coding & noncoding regions of the human genome.

The Translational Neurogenomics Research Group is led by Associate Professor Seo-Kyung Chung.