Centre for Kidney Research
This page is a research page. For clinical information, please view our nephrology service page on the Sydney Children's Hospitals Network website.
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The Centre for Kidney Research (CKR) is a national and international network of expert teams, incorporating the research arm of the nephrology clinical service based at The Children's Hospital at Westmead. Our academic, clinical and laboratory teams work together, focusing on nephrology, biostatistics, epidemiology, health economics and psychology.
We are integrated into several national and international collaborations hosting teams including:
- Academic Renal Team (ART)
- Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD)
- Biostatistics Team
- Caring for Australian and New Zealanders with Kidney Impairment (CARI) Guidelines
- Laboratory
- Standardised Outcomes in Nephrology (SONG)
Objectives
We aim to identify causes, treatments, prevention and management of a range of kidney diseases, and to evaluate the evidence for current treatments.
- Our clinical research areas are Aboriginal and Indigenous health, evidence synthesis, priority populations health and patient centred care.
- Our laboratory research focuses on improving our understanding of patients with kidney disease through immunology, genetics, advanced therapeutics and other novel therapies.
- Our academic team enable clinical knowledge and training for the next generation of researchers, working in areas of laboratory studies, clinical trials, registries and PhD supervision.
Impact
- We have established which early markers of chronic kidney disease have most influence on the trajectory of chronic disease and the target age range for early prevention programs in Aboriginal and Indigenous children (ARDAC).
- We have produced and implemented clinical practice guidelines on the management of kidney disease in both adults and children to health professionals across Australia and New Zealand. Resulting in improved evidence-based care for patients and cost savings to the health system.
- We are leading a phase 2 study to understand how genetics, social conditions and the environment work together to contribute to the major health challenges experienced by children and young people with chronic kidney disease (KCAD).
- We are assessing the health benefits and costs of a patient navigator program for children with chronic kidney disease experiencing low socioeconomic status or living in remote areas (NAVKIDS2).
- We are leading a multi-centre trial assessing the efficacy and safety of immune treatments to children who received kidney transplants (TACKLE-IT).
Collaborators
- Antecedents of Renal Disease in Aboriginal Children (ARDAC) (opens in a new tab)
- Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) (opens in a new tab)
- Australasian Kidney Trials Network (AKTN) (opens in a new tab)
- Cochrane Kidney and Transplant (CKT) (opens in a new tab)
- KidGen (opens in a new tab)
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Prof Allison Jaure
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Biography
Director - Clinical. Allison Jaure (nee Tong) is a Principal Research Fellow and holds an Australian NHMRC Investigator Award. She has an interest in patient involvement in research, like research priority setting, research core outcomes development and clinical trial co-production.
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Prof Stephen Alexander
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Biography
Director - Laboratory. Stephen Alexander is a Senior Staff Specialist paediatric nephrologist, Conjoint Professor Paediatrics at the University of Sydney, and the Director CKR Laboratory. His research group studies mechanisms of tolerance in transplantation and kidney disease.
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Prof Armando Teixeira-Pinto
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Biography
Director - Clinical. Armando Teixeira-Pinto is a Professor of Biostatistics at the University of Sydney and Co-leader of the Centre for Kidney Research. He obtained his PhD in Biostatistics in 2007, from Harvard University and joined the University of Sydney in 2012.
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Prof Germaine Wong
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Biography
Director - Clinical. Prof Wong is an academic transplant nephrologist, the Director of Western Renal Service at Westmead Hospital, Professor of Clinical Epidemiology, NHMRC Leadership Fellow at the University of Sydney.
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Dr David Tunnicliffe
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Biography
Director –Clinical. David Tunnicliffe is a Senior Research Fellow and a NHMRC Emerging Leader. His interest is the translation of evidence to improve outcomes for those with chronic kidney disease. He is the Scientific Director of the Australian and New Zealand Guideline Developer for kidney disease (CARI Guidelines).
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